ALS is a progressive disease caused by the degeneration of neurons, the nerve cells in the central nervous system that control muscle movement. As a neuron disease, the disorder causes muscle weakness and atrophy throughout the body as both the upper and motor neurons degenerate, ceasing to send messages to muscles. Unable to function, the muscles gradually weaken, develop fasciculations (twitches) because of denervation, and eventually atrophy because of that denervation...
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