Description

Suhagra, a brand of sildenafil citrate, is a medication primarily used for treating erectile dysfunction (ED) and pulmonary arterial hypertension. It functions as a phosphodiesterase type 5 (PDE5) inhibitor, promoting relaxation of smooth muscle tissue and enhancing blood flow to specific areas of the body. Suhagra tablets come in various dosages, including Suhagra 25 mg, Suhagra 50 mg, and Suhagra 100mg, catering to different therapeutic needs.

Pharmacology: Sildenafil, the active ingredient in Suhagra, is a phosphodiesterase type 5 (PDE5) inhibitor. By inhibiting PDE5, sildenafil increases cyclic guanosine monophosphate (cGMP) levels in the corpus cavernosum, leading to smooth muscle relaxation and inflow of blood to the corpus cavernosum, which facilitates an erection in the presence of sexual stimulation.

Efficacy Assessment: Clinical trials have demonstrated the efficacy of sildenafil in treating ED. The efficacy is typically assessed through patient-reported outcomes, such as improvement in erection hardness and maintenance, and the ability to successfully engage in sexual activity.

However, it's important to note that Suhagra or any sildenafil-based medication should only be taken under the guidance of a healthcare provider. It's not suitable for everyone, and there are potential side effects and interactions with other medications.

General Instructions

When using Suhagra pills, it's important to follow medical advice closely. The medication, especially Suhagra 100 or Suhagra 50mg, should be taken approximately one hour before the intended sexual activity. Suhagra 25 mg serves as a milder option, often suitable for individuals seeking a lower dose. Its effects can last for up to four hours. Patients should not take more than the recommended dose or take it more than once daily.

Side Effects

The use of Suhagra, including Suhagra 50 and Suhagra 100mg tablets, can lead to side effects such as headaches, flushing, dyspepsia, and visual disturbances. Rare but serious adverse effects like priapism and sudden hearing loss have been reported. In some cases, sildenafil can lead to significant cardiovascular events or interactions with other medications.

Inform Your Doctor If You Have Experienced Any of the Following Conditions:

  • Heart problems (e.g., angina pectoris, chest pain, heart failure, heart rhythm disturbances, heart attack, or aortic valve constriction)
  • Recent stroke or myocardial infarction (within the past 6 months)
  • Low or high blood pressure
  • Severe vision disorders
  • Congenital disease of the eyes (retinitis pigmentosa)
  • Kidney diseases or liver disorders
  • Blood problems, including leukemia
  • Allergy to Sildenafil or other ingredients in Suhagra
  • Penis deformity or Peyronie’s disease
  • Condition of having an erection that lasted for more than 4 hours
  • Ulcerative bleeding or any other bleeding
  • Use of any other medications

Uses

Suhagra is used primarily to treat erectile dysfunction. It helps achieve and maintain an erection sufficient for sexual activity. It's also prescribed for pulmonary arterial hypertension to improve exercise capacity and delay clinical worsening.

Regulatory Compliance and Patenting: As with all pharmaceuticals, sildenafil and its formulations like Suhagra must comply with regulatory guidelines set by agencies like the FDA or EMA.

Concerns

While evaluating treatment options, including Suhagra 50mg or Suhagra 100mg, patients with pre-existing health conditions, particularly heart diseases, should consult their healthcare provider. Patients with cardiovascular conditions should exercise caution when using Suhagra. It's also not recommended for individuals taking nitrates or those with known allergies to sildenafil.

What is Suhagra?

Suhagra is a medication commonly used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, an active ingredient similar to that in Viagra, which helps in achieving and maintaining an erection.

How does Suhagra work?

Suhagra works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which increases blood flow to the penis and helps in producing an erection during sexual stimulation.

What is the recommended dosage of Suhagra?

The recommended starting dose of Suhagra is usually 50 mg, taken approximately one hour before sexual activity. Depending on effectiveness and tolerance, the dose may be increased to 100 mg or decreased to 25 mg.

What are the side effects of Suhagra?

Common side effects of Suhagra include headaches, flushing, stomach upset, nasal congestion, dizziness, and blurred vision. Rare but serious side effects can include priapism, sudden hearing loss, and heart attack symptoms.

Can Suhagra be taken with alcohol?

Alcohol should be consumed with caution when taking Suhagra, as it can increase the likelihood of side effects and can reduce the effectiveness of the medication.

How long does the effect of Suhagra last?

The effects of Suhagra can last for up to 4-6 hours, but this can vary depending on individual factors such as metabolism, age, and other health conditions.

Is Suhagra safe for everyone?

Suhagra is not suitable for everyone, especially those with certain medical conditions or those taking certain medications. Consult with a healthcare provider before using Suhagra.

Does Suhagra require a prescription?

Yes, Suhagra is a prescription medication. A consultation with a healthcare provider is essential to determine if it's an appropriate treatment for your condition.

Can Suhagra be used to treat conditions other than ED?

While Suhagra is primarily used for ED, sildenafil citrate can also be used to treat other conditions like pulmonary arterial hypertension (PAH). However, it should only be used for these conditions under the guidance of a healthcare provider.

Can Suhagra be taken with food?

Suhagra can be taken with or without food, but taking it with a heavy meal may delay the onset of its effects.

When Not to Use?

Suhagra should not be used in conjunction with nitrates, certain antihypertensives, and recreational drugs known as “poppers”. It's contraindicated in patients with a history of non-arteritic anterior ischemic optic neuropathy (NAION) or those with severe hepatic impairment.

Warnings

Patients should be aware of the potential for interactions with other medications, such as alpha-blockers or antihypertensives. Suhagra can cause a drop in blood pressure, and its use should be discussed with a healthcare provider, especially for those with pre-existing cardiovascular conditions.

Dosage

Suhagra is available in various dosages, including 25 mg, 50 mg, and 100 mg. The initial recommended dose is typically 50 mg, adjusted based on efficacy and tolerability. The maximum recommended dosing frequency is once per day.

Interactions

Suhagra can interact with several medications, including nitrates used for chest pain, alpha-blockers, HIV protease inhibitors, and other drugs used for ED. It can also interact with certain foods and alcohol.

Other Details

Patients should store Suhagra at room temperature, away from moisture and heat. It should be kept out of reach of children.

References

  1. Byoun, H., Lee, Y.-J., & Yi, H. (2010). Subarachnoid Hemorrhage and Intracerebral Hematoma due to Sildenafil Ingestion in a Young Adult. Journal of Korean Neurosurgical Society. Link
  2. Sanphui, P., Tothadi, S., Ganguly, S., & Desiraju, G. (2013). Salt and cocrystals of sildenafil with dicarboxylic acids: solubility and pharmacokinetic advantage of the glutarate salt. Molecular Pharmaceutics. Link
  3. Al-shdefat, R., Ali, B. E., Anwer, M., Fayed, M. H., Alalaiwe, A. S., & Soliman, G. A. (2016). Sildenafil citrate-Glycyrrhizin/Eudragit binary spray dried microparticles: A sexual behavior studies on male rats. Journal of Drug Delivery Science and Technology. Link
  4. Viagra.com. (2021). ED Treatment. Link
  5. Goldstein, I., Burnett, A., Rosen, R., Park, P., & Stecher, V. (2019). The Serendipitous Story of Sildenafil: An Unexpected Oral Therapy for Erectile Dysfunction. Sexual Medicine Reviews

General Information

Breast cancer is the most common type of tumors among the female population of Europe, America and some Asian countries. Annually, more than one million cases of this disease are registered in the world, and with an average life expectancy of 80 years the risk of developing breast cancer is 12.5%. Over the past 20 years, there has been a steady increase in the incidence of this type of cancer in the whole world, as well as in Russia, especially in cities and megacities. Since 1985, takes the first place among women’s oncological diseases, accounting for 31.2% of the total. It is well known that an annual preventive examination contributes to the early detection of tumors. However, often patients refer to a doctor already suffering from obvious signs of a tumor, and this complicates the subsequent treatment. One of the reasons of that is the lack of understanding of the importance of early diagnosis of the disease. Now scientists have deeply penetrated into the mechanisms of the origin of the cancer cell, although much remains unclear. Like other cancers, breast cancer is insidious and aggressive. Therefore, it is very important for any person to have an idea of the development of this disease: forewarned is armed. (more…)

Description

Eriacta, a pharmaceutical product, contains the active ingredient Sildenafil Citrate, primarily used to treat erectile dysfunction (ED) in adult men. Sildenafil, classified as a phosphodiesterase type 5 (PDE5) inhibitor, works by enhancing the effects of nitric oxide (NO), a natural chemical the body produces that relaxes muscles in the penis. Available in Eriacta 100mg tablets, it functions by increasing blood flow to the penis to help a man get and keep an erection.

General Instructions

Eriacta should be taken as advised by a healthcare provider. The usual dosage is Eriacta 100mg, taken orally with water, about 30 minutes to an hour before planned sexual activity. The tablet is to be swallowed whole with water and can be taken with or without food. However, a high-fat meal may delay the drug's onset.

Side Effects

Common side effects include headaches, flushing, upset stomach, and dizziness. Temporary visual changes, such as increased sensitivity to light or blurred vision, may also occur. Rarely, Eriacta can lead to more severe side effects like priapism (prolonged and painful erection), hearing loss, or heart problems. Immediate medical attention is required for these severe side effects.

Eriacta, which is Sildenafil – containing medication, does not cause serious side effects.

Sildenafil-based drugs use can cause the following adverse reactions:

  • Dizziness;
  • Feeling of heat;
  • Drop in blood pressure;
  • Anemia;
  • Tremor (shaking lower and upper limbs);
  • Burning sensations and increased sensitivity of the skin;
  • Insomnia, anxiety;
  • Impaired visual function;
  • Inflammation of the cornea of the eye;
  • Impairment of hearing;
  • Cough and obstruction of the upper respiratory tract;
  • Bloating;
  • Dry mouth;
  • Pain in the muscles and back;
  • Increased body temperature;
  • Puffiness.

Uses

Eriacta is used for the treatment of erectile dysfunction. It helps in achieving and maintaining an erection but does not cure ED or increase sexual desire. Sexual stimulation is still required for Eriacta to work.

Concerns

Patients with cardiovascular disease, a history of stroke or heart attack, or high or low blood pressure should use Eriacta cautiously. It's also not recommended for those with severe liver or kidney impairment. It's also important to consider the medication's interaction with other treatments the patient may be undergoing. It's also not recommended for individuals allergic to sildenafil.

What is Eriacta?

Eriacta is a medication used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, which is the same active ingredient found in Viagra. Eriacta helps in achieving and maintaining an erection by increasing blood flow to the penis.

How does Eriacta work?

Eriacta works by inhibiting the phosphodiesterase type 5 (PDE5) enzyme, leading to increased blood flow to the penis, which facilitates an erection when sexually aroused.

What is the recommended dosage of Eriacta?

The recommended starting dose of Eriacta is usually 50 mg, taken about one hour before sexual activity. Depending on the effectiveness and tolerability, the dosage can be adjusted to a maximum of 100 mg or reduced to 25 mg.

What are the side effects of Eriacta?

Common side effects of Eriacta include headaches, flushing, indigestion, nasal congestion, dizziness, and blurred vision. Rare but serious side effects can include priapism, sudden hearing loss, and heart attack symptoms.

Can Eriacta be taken with alcohol?

Alcohol should be used with caution while taking Eriacta, as it can increase the likelihood of side effects and can impair the ability to achieve an erection.

How long does the effect of Eriacta last?

The effects of Eriacta can last for up to 4-6 hours, but this can vary depending on individual factors such as metabolism, age, and other health conditions.

Is Eriacta safe for everyone?

Eriacta is not suitable for everyone, especially men with certain medical conditions or those taking certain medications. Consultation with a healthcare provider is essential before using Eriacta.

Does Eriacta require a prescription?

Yes, Eriacta is a prescription medication. A healthcare provider should be consulted to determine if it is appropriate for your condition.

Can Eriacta be used to treat conditions other than ED?

While primarily used for ED, sildenafil citrate, the active ingredient in Eriacta, is also used to treat other conditions like pulmonary arterial hypertension. However, its use for other conditions should be under medical guidance.

Can women use Eriacta?

Eriacta is not recommended for use by women. It is specifically designed for treating erectile dysfunction in men.

When Not to Use

Eriacta should not be used by individuals allergic to sildenafil. It's also contraindicated in patients using nitrate drugs for chest pain or heart problems, as this combination can lead to a dangerous drop in blood pressure. Additionally, it should not be used in conjunction with nitrate medications, often prescribed for chest pain, as this can cause a dangerous drop in blood pressure.

Warnings

Eriacta should be used with caution in patients with heart conditions or peptic ulcer disease. It's important to discuss all medical history with a healthcare provider before starting Eriacta. Sudden vision loss in one or both eyes, a rare condition called NAION, has been reported in patients taking PDE5 inhibitors, including sildenafil. Eriacta should not be taken more than once a day. Patients should seek immediate medical attention if they experience a sudden loss of vision or an erection that lasts more than 4 hours.

Eriacta® (Sildenafil Citrate) is a medical product and requires careful attitude to it. It cannot be taken by men diagnosed with serious diseases of the cardiovascular system, due to possibility of drop in blood pressure causing loss of consciousness or even death. This tablet should not be taken by men diagnosed with liver and kidney disease. These pills are contraindicated in case of determined oncology disease, and therefore it is better to use safer treatment. It should not be taken in case of individual intolerance to the medication components.

Also this product should not be used by persons under 18 years old, by women, including pregnant and breast-feeding females, as well as by persons with pronounced nervousness or excitability. Moreover, Eriacta is forbidden to persons suffering from Peyronie's disease; acute forms of diseases of the gastrointestinal tract; sickle-cell anemia and any other pathology accompanied by bleeding.

Dosage

The recommended starting dose is Eriacta 100mg, but this may be adjusted based on individual efficacy and tolerability. The maximum recommended dosing frequency is once per day.

Initial safe daily dose of Sildenafil-containing medication is 50 mg. But at the same time maximum daily dose should not exceed 100 mg! Sildenafil – based preparations are taken once a day. Patients in old age should take the drug in the previously described dosage.

Overdose

  • In case of a Sildenafil (Eriacta) based drug overdose there should be prescribed medicines intended to reduce all of the listed symptoms.
  • In order to avoid next possible discomfort of Eriacta overdose the patient is recommended to take a half of the dose. In some cases, even a quarter of the tablet can be enough.

Interactions

Eriacta can interact with certain medications such as nitrates, some antibiotics, antifungals, as well as drugs used to treat high blood pressure and HIV/AIDS. Alcohol consumption should be limited as it can increase side effects.

The Eriacta should be combined with alcohol. This interaction reduces the product effectiveness, and increases the risk of adverse reactions and also can result in feeling unwell.

Sildenafil is not allowed to be taken concomitantly with preparations based on nitric oxide, nitrates and nitrites. This remedy also cannot be taken with such inhibitors of the CYP3A4 isoenzyme as Erythromycin, Ketoconazole, Nefazodone and others as well as some other medications against pulmonary arterial hypertension.

Concomitant administration of Eriacta with drugs affecting the CYP3A4 isoenzyme can result in a considerable prolongation in its action duration. There is no any interaction when this drug is coadministered with antacid agents.

In addition, simultaneous administration with adrenergic blocking agents can cause a drop in blood pressure, which in turn can result in dizziness. Furthermore, it can also provoke bleeding.

The following medicines also do not impact the Sildenafil activity: Warfarin; antidepressants; diuretics; hypotensive drugs (for example, Diroton, Amlodipine, etc.); Azithromycin (Sumamed).

The patient does not need to correlate the medicine and food intake as the food does not affect the effectiveness or speed of the remedy action.
However, this remedy cannot be combined with eating fatty foods, since this can weaken the effect of the agent action.

Other Details

In the age of nanotechnology, computer technology, the latest developments in various industries, and against the background of city smoke and instability of the environment, disorders of the male sexual system became very frequent. The erectile dysfunction is usually a result of stresses, troubles of any origin, overwork. Medicine industry has an effective remedy to treat sexual function disorders.

It is interesting that these days the Sildenafil-based generics available in the worldwide trade are produced all over the world. Most of all generics are manufactured in the European Union countries and India. As for pharmacokinetics we can say that profiles of all generics, as a rule, are similar to the profiles of original molecule in terms of excretion; the number of adverse reactions is also approximately same and averaged from 10.9 to 17% and action time lasts for 4-5 hours. Indications as well as contraindications for Sildenafil-containing products are similar. It ought to be said that these days exists adapted for women Sildenafil (Eriacta). It was designed for use by women suffering from tough vaginal dryness, anorgasmia and other diseases. The only thing has to be mentioned that clinical response of the medicine was not proven so far. What interesting is that other generics are restricted to use in women. There are articles, in particular, for example, dedicated to Eriacta (Sildenafil), reporting about its positive effect on the qualitative profile of spermatozoa. It was found that in small doses this agent is really capable to boost the activity of spermatozoa of A + B categories, but when a dosage is more than 250 mg it causes a hyper inhibitory action. According to the histological study a long-term use of Sildenafil-containing remedies does not affect cells of seminiferous epithelium.

Among existing Sildenafil generics such product as Eriacta currently presents an interest. This preparation has excellent properties. It is able to enhance and even restore an erection function disorder forever. This medication practically does not have contraindications; it is easily and quickly removed from the body. The conducted studies results show that its effectiveness and safety are comparable with the original remedy. During studies a significant positive impact on the erectile function and all components of overall sex satisfaction have been evidenced, which positively affected the quality of life of patients using Eriacta. Moreover, a safety profile of the remedy shows that such adverse reactions as headache and skin redness was lower compared to the original medicine. Also, a positive impact of the medicine on spermatogenesis was evidenced, and its price corresponds to other analogues.

Sildenafil (Eriacta) has been successfully used in the erectile dysfunction treatment in patients having different pathology in both mono- and combined therapy. It can be used in patients with various somatic diseases, and the conducted clinical trials results open new prospects for its application.

How does Eriacta ( such as cenforce 100kamagra 100suhagra 100revatio 20 mg ) work: the medicine raises the blood level in the penis, which helps the man to get sexual arousal in natural manner. The product starts its action during natural sexual arousal, and at the end of sexual intercourse the sexual organ comes to a state of relaxation. In other words, the drug affects only on the natural mechanisms of erection. The remedy begins to act in 40-50 minutes after intake. Duration of its action can vary from 5 to 7 hours, depending on the situation.

Eriacta does not protect against sexually transmitted infections, including HIV. It is not indicated for use in women, children, or adolescents.

References

  1. Cheitlin, M. D., Hutter, A. M., Brindis, R. G., Ganz, P., Kaul, S., Russell, R. O., Zusman, R. M. (1999). “Use of Sildenafil (Viagra) in Patients With Cardiovascular Disease.” Journal of the American College of Cardiology, 33(1), 273-282. Available at: U.S. National Library of Medicine.
  2. Mayo Clinic Staff. (2021). “Erectile Dysfunction.” Mayo Clinic. Retrieved from Mayo Clinic.
  3. Montorsi, F., McDermott, T. E., Morgan, R., Olsson, A., Schultz, A., Kirkeby, H. J., Osterloh, I. H. (1999). “Efficacy and Safety of Fixed-Dose Oral Sildenafil in the Treatment of Erectile Dysfunction of Various Etiologies.” Urology, 53(5), 1011-1018. Available at: ScienceDirect.
  4. “Drug Interaction Checker.” (2023). Drugs.com. Retrieved from Drugs.com.
  5. Goldstein, I., Lue, T. F., Padma-Nathan, H., Rosen, R. C., Steers, W. D., Wicker, P. A. (1998). “Oral Sildenafil in the Treatment of Erectile Dysfunction.” New England Journal of Medicine, 338(20), 1397-1404. DOI: 10.1056/NEJM199805143382001.
  6. Webb, D. J., Freestone, S., Allen, M. J., Muirhead, G. J. (1999). “Sildenafil Citrate and Blood-Pressure-Lowering Drugs: Results of Drug Interaction Studies with an Organic Nitrate and a Calcium Antagonist.” American Journal of Cardiology, 83(5), 21C-28C. DOI: 10.1016/S0002-9149(99)00044-2.

Description

Priligy, known generically as Dapoxetine, is a selective serotonin reuptake inhibitor (SSRI) used primarily for the treatment of premature ejaculation in adult males. It is available in forms such as Priligy 30mg tablets and Priligy 60 mg tablets. It is recognized for its rapid onset of action and unique property as an as-required treatment, distinguishing it from other therapies in its class.

Pharmacological Profile

  • Class: Priligy belongs to the class of selective serotonin reuptake inhibitors (SSRIs). While SSRIs are commonly used as antidepressants, Priligy is used specifically for PE due to its unique pharmacokinetic properties.
  • Mechanism of Action: Dapoxetine works by inhibiting the serotonin transporter, leading to increased serotonin's action at pre- and postsynaptic receptors. Enhanced serotonin activity plays a key role in delaying ejaculation.

Drug Development and Efficacy

  • Development: The development of Priligy was focused on creating a fast-acting SSRI, suitable for on-demand use rather than continuous treatment.
  • Efficacy: Clinical trials have demonstrated that Priligy can significantly increase intravaginal ejaculatory latency time (IELT), improving control over ejaculation and reducing distress related to PE.

The pharmacological efficacy of Priligy (Dapoxetine) is characterized by several notable advantages in the therapeutic management of premature ejaculation:

  • Efficacy in Delaying Ejaculation: Clinical evidence supports the efficacy of Priligy in substantially delaying the occurrence of ejaculation, thereby mitigating the symptoms of premature ejaculation.
  • Prophylactic Use: It is suggested to consider Priligy for prophylactic use in individuals predisposed to premature ejaculation, to proactively manage this condition.
  • Extended Duration of Sexual Intercourse: Clinical trials have demonstrated that the use of Priligy can significantly extend the duration of sexual intercourse, often by threefold or more, enhancing sexual satisfaction.

General Instructions

Priligy should be consumed orally 1-3 hours before anticipated sexual activity, with the recommended starting dose being 30mg. It can be increased to Priligy 60 mg based on individual response and tolerability. It is available as Priligy 30mg and Priligy 60mg doses. Patients should start with the lower dose and can adjust based on their response and tolerance. It's not intended for continuous daily use.

Side effects

Common side effects of Priligy include nausea, headache, dizziness, and diarrhea. Most side effects are mild to moderate and transient. However, patients should be aware of the potential for fainting and should sit or lie down if they feel lightheaded or dizzy. However, severe side effects like fainting should be immediately reported to a healthcare provider.

Uses

Priligy is used for the treatment of premature ejaculation in men aged 18-64 years. The mechanism of action of Priligy involves its active ingredient dapoxetine, which acts upon specific serotonin receptors in the brain. This action modulates the neural pathways responsible for ejaculation. Its effectiveness lies in increasing the time to ejaculation and improving control over ejaculation, leading to a delay in ejaculation onset and a consequent increase in the duration of sexual intercourse.

Distinctively, Priligy demonstrates a rapid onset of action post-administration, distinguishing it from other similar medications which may take up to two weeks to manifest therapeutic effects.

Concerns

Patients with a history of cardiac conditions should use Priligy with caution. Those with a history of fainting or patients taking certain medications may be at increased risk of side effects. It's important to discuss your full medical history with a healthcare provider before starting Priligy dapoxetine.

What is Priligy?

Priligy is a medication used to treat premature ejaculation (PE) in men. It contains the active ingredient dapoxetine, which is a short-acting selective serotonin reuptake inhibitor (SSRI).

How does Priligy work?

Priligy works by increasing the activity of serotonin in the nervous system. Serotonin is a neurotransmitter that is involved in passing messages between nerve cells. It has various functions, including regulating the ejaculation process.

Who can use Priligy?

Priligy is prescribed for adult men aged 18 to 64 who have all of the following: a history of premature ejaculation, poor control over ejaculation, and a marked personal distress or interpersonal difficulty as a result of PE.

What is the recommended dosage of Priligy?

The recommended starting dose of Priligy is 30 mg, taken 1 to 3 hours before sexual activity. If the effect is insufficient and the side effects are acceptable, the dose may be increased to the maximum recommended dose of 60 mg.

What are the side effects of Priligy?

Common side effects of Priligy include dizziness, headache, nausea, diarrhea, insomnia, and fatigue. These side effects are usually mild to moderate in intensity and temporary.

How quickly does Priligy take effect?

Priligy is usually taken 1 to 3 hours before sexual activity. It can work quickly, often within 1 hour, but its effectiveness may vary from person to person.

Can Priligy be taken with alcohol?

Alcohol should not be consumed when taking Priligy as it can increase the risk of fainting and other side effects. It may also increase the risk of injury from fainting.

Is a prescription required for Priligy?

Yes, Priligy is a prescription medication. It's important to consult with a healthcare provider to ensure it's safe and suitable for you to use.

Can Priligy cure premature ejaculation permanently?

Priligy is not a cure for premature ejaculation but a treatment to manage the condition. It helps to prolong the time taken to ejaculate and can improve control over ejaculation.

Can Priligy be taken with other medications?

Priligy can interact with certain medications, so it's important to inform your healthcare provider about all medications you are currently taking, including over-the-counter drugs and supplements.

When not to use?

Priligy is contraindicated in patients with hypersensitivity to dapoxetine HCL or any other component of the formulation. It should not be used in conjunction with recreational drugs or alcohol. It's also advised against in individuals with significant psychiatric or cardiac conditions.

Warnings

Priligy can cause orthostatic hypotension. Patients should be warned about the possibility of syncope and other side effects such as visual disturbances. Priligy should be used with caution in patients with mild or moderate renal impairment and is not recommended for those with severe renal impairment.

Dosage

The recommended starting dose is Priligy 30mg, taken as needed approximately 1 to 3 hours prior to sexual activity. Depending on individual efficacy and tolerability, the dose may be increased to 60 mg. The maximum recommended dosing frequency is once every 24 hours.

Interactions

Priligy should not be used with monoamine oxidase inhibitors or serotonin reuptake inhibitors, as it may increase the risk of serotonin syndrome. Caution is advised when taken with medications affecting hepatic metabolism.

Other details

Clinical trials have shown that Priligy, combined with behavioral therapy and psychological counseling, may further enhance its effectiveness. Patients are advised to discuss with their healthcare provider for personalized advice.

References

  1. Chaplin, S., & Mostyn, P. (2014). Dapoxetine: licensed treatment for premature ejaculation. Prescriber, 25. Link
  2. Cai, D., et al. (2020). [Priligy combined with behavioral therapy and psychological counseling for primary premature ejaculation]. Zhonghua nan ke xue = National journal of andrology, 26(7), 611-615. Link
  3. Kowey, P., et al. (2011). Cardiovascular Safety Profile of Dapoxetine during the Premarketing Evaluation. Drugs in R&D, 11, 1 – 11. Link
  4. Modi, N., et al. (2006). Single‐ and Multiple‐Dose Pharmacokinetics of Dapoxetine Hydrochloride, a Novel Agent for the Treatment of Premature Ejaculation. The Journal of Clinical Pharmacology, 46.
  5. Qoctor. 2021. Premature Ejaculation Patient Information Leaflet. Link
  6. Mirone, V., et al. (2014). Results from a prospective observational study of men with premature ejaculation treated with dapoxetine or alternative care: the PAUSE study. European urology, 65(4), 733-9. Link
  7. Medicines.org.uk. 2021. Priligy 30 mg film-coated tablets – Summary of Product Characteristics (SmPC) – (emc). Link

General Information

Levothyroxine Sodium is the first commercial synthetic medicine for treatment of thyroid gland dysfunction in the USA which was firstly presented at the market in 1955 under the name Synthroid by Laboratory Flint. This medicine has a long story of medical use in the USA and at the international level, and for a long time it was the most popular medicine to combat hypothyroidism. Figures show that this brand provided 85% of the general sales of Levothyroxine and the revenues of medicine sale make $600 Mio. Among sportspeople, however, the medicine Cytomel is more popular because it’s faster and more effective. As this remedy is considered as a weaker medicine of slower action, for achievement of similar results it’s necessary to take it during a longer period of time. (more…)

General Information

Syphilis is caused by the Treponema pallidum bacterium. As soon as it is there in the body, it gradually starts affecting all organs. At the same time, Treponema dies outside of the organism very quickly. Disinfectants, detergents and even ordinary sunlight produce a destructive impact on it. This bacterium can survive for a long time only in moist conditions and when frozen. Infection is transmitted not only through sexual, but also non-sexual contact, and at advanced stages it can provoke irreversible disorders of the nervous system, bone structure we well as of the skin. Earlier, the congenital forms of this disease were often diagnosed, meaning that the child was infected already in the womb. There were records of cases of infection with the blood transfusion from a sick person. These days such kind of infection is very rare. Pregnant women must make a test, and the blood before a transfusion is carefully checked for all infections. (more…)

General Information

Generic Cipro (Ciprofloxacin) is an Anti-Infective Medicine. It is a medicine from the group of fluoroquinolones. This drug is usually prescribed more often than other antibacterial medicines. (more…)

General Information

For a rather long time doctors did not recognize the existence of such disease as fibromyalgia, considering complaints of patients as manifestations of mental health disorder. It is a terrible disease, which is associated with symmetric or asymmetric pain in various parts of the patient’s body, making him suffer practically all the time. The main paradox was that it was completely unclear, whether the pain is caused by some psychological factors or depression and similar problems in patients, which are caused by the permanently aching body they have to bear. Earlier this disease was frequently misdiagnosed because old methods of examination have not shown proper results: no signs of sarcitis or osseous tissue inflammation, no symptoms of nerve disorders and manifestations of arthritis, myositis, etc. However, in recent years interest in this neurological disease has increased due to increase in the incidence rate approximately by 5%. (more…)

Lasix (Furosemide) is a derivative of sulfonamide, a diuretic agent. It inhibits sodium and chlorine ions reabsorption. This medicine has an expressed diuretic, natriuretic, chlorouretic effect and increases excretion of potassium, calcium and magnesium ions. (more…)

General information

The absence of sexual attraction in women is not only about the hormones, but a psychological problem as well. Any hormone imbalance and psychological stress can provoke sexual dysfunction. Sexual interest may fade away in women of any age. (more…)