Desyrel, which has trazodone as a main active ingredient, is sold under many different brand names around the world. It is a strong antidepressant that doubles up as a common sleep drug. The drug falls under the SARI (serotonin antagonist and reuptake inhibitor) class. This class of drugs works by increasing the level of serotonin in our system. This in turn leads to a healthy mental balance.

Desyrel has long been used as an off-label treatment for insomnia. In fact, there is a great deal of anecdotal market evidence showing that Desyrel is more widely used as an insomnia treatment drug than an antidepressant.

How Desyrel works for insomnia treatment?

Trozodone is most effective in the treatment of insomnia when it is administered in lower doses. It is suggested that the lower dosage targets the H1 histaminergic receptor as an antagonist. This in turn reduces the effects of histamine and leads to drowsiness.

Using Desyrel as treatment for insomnia

Apart from the fact that it actually works, there are some other benefits associated with using Desyrel as an off-label treatment for insomnia. First of all, the drug is rather cheap. Generally it comes at a much lower cost than most of the regular sleeping pills.

Reports show that using trozodone to fight withdrawal induced insomnia is a highly effective method of treatment. Patients suffering from alcohol, substance or antidepressant withdrawal tend to get cases of insomnia that come as a result of that withdrawal. In most cases, this can cause agitation, frustration and even relapse. Desyrel is believed to be effective in cases like that. Market research suggests that taking one small dose of trozodone before bed can, in most cases, help the patient to fall asleep.

This drug is a non-controlled substance. However, most sleeping pills fall under the ‘controlled substances’ umbrella which means that they have a great potential for abuse.

Special instructions

As a form of treatment for insomnia, trozodone has proven to be quite effective. Studies have shown that the patients taking this drug specifically to combat insomnia often feel the effects within the first 2 weeks.

Desyrel is often used for the treatment of insomnia when the drugs such as Lunesta and Ambien have failed. Market research shows that the effects of this drug on insomniacs are not only positive, but sustainable and effective as well.

However, it should be remarked that “officially” Desyrel is an antidepressant, and has not yet been approved by FDA (Food and Drug Administration) as a soporific.