At a glance

  • For FDA-approved sildenafil, the timing is documented: peak levels 30–120 minutes after a dose, a half-life of about 4 hours, and an effect on erections shown up to about 4 hours, weaker at 4 hours than at 2.
  • Common side effects – headache, flushing, indigestion, vision tint – rise with dose.
  • For Kamagra, none of this has been verified: its content is unchecked, so how long it lasts and what side effects it causes cannot be predicted.
  • Approved sildenafil did not affect sperm motility or shape after a single 100 mg dose; no such data exist for Kamagra.

How sildenafil works

Sildenafil blocks PDE5, an enzyme that limits blood flow to the penis; with sexual stimulation, this allows an erection. Without stimulation, it has no effect.[1]

How long approved sildenafil lasts

Timing of FDA-approved sildenafil (Viagra label)
MeasureValue
TakenAbout 1 hour before sex; 30 minutes to 4 hours before
Peak blood level30–120 minutes (median 60) on an empty stomach
High-fat mealDelays peak by about 60 minutes
Half-lifeAbout 4 hours
Effect on erectionsShown up to about 4 hours, weaker at 4 than at 2 hours
Blood-pressure effectLargest 1–2 hours after dose, gone by 8 hours

All values from the Viagra prescribing information.[1] For comparison, tadalafil (Cialis) lasts much longer – see Viagra vs. Cialis.

Side effects of approved sildenafil

Most common side effects by dose (Viagra label)
Side effect25 mg50 mg100 mgPlacebo
Headache16%21%28%7%
Flushing10%19%18%2%
Indigestion3%9%17%2%
Abnormal vision1%2%11%1%
Serious effects[1]
EffectLevelAction
Erection longer than 4 hours■ EmergencyEmergency care
Sudden vision or hearing loss■ EmergencyStop and get care at once
Chest pain during sex■ EmergencyStop and get help
Taken with nitrates or riociguat■ EmergencyNever – dangerous drop in blood pressure

Full guide: sildenafil side effects.

Sperm and fertility

In healthy volunteers, a single 100 mg oral dose of sildenafil had no effect on sperm motility or morphology. These data come from approved sildenafil of known strength; no comparable data exist for Kamagra.[1][2]

What stays unknown for Kamagra

Verified data: approved sildenafil vs Kamagra (October 2026)[1][2][3][4]
QuestionFDA-approved sildenafilKamagra
Amount of active ingredient per tabletCheckedSeller’s claim only
Onset and durationIn the FDA labelNo reviewed data
Side-effect profileFrom trials and monitoringDepends on actual content
Effect on spermNo effect in a single-dose studyNot studied
Record in FDA databasesYesNone

FDA warns that medicines from unlicensed sellers can contain too much or too little active ingredient, the wrong ingredient or none at all – which changes both how long a product works and what it does.[3]

Questions people ask

How long does Kamagra last?

Unknown – it has never been reviewed. Approved sildenafil’s effect was shown up to about 4 hours.

How long does Viagra take to work?

About an hour; peak levels come 30–120 minutes after a dose, later after a high-fat meal.

Does Kamagra have the same side effects as Viagra?

Only if it really contains the same dose of sildenafil – which is unverified.

Does sildenafil affect sperm?

Not in the available study: a single 100 mg dose had no effect on sperm motility or shape.

Can I take a second dose if it wears off?

No. Approved sildenafil is taken no more than once a day.

What is the legal alternative?

FDA-approved generic sildenafil, the same medicine as Viagra, with a prescription.

Conclusion: what we know, what we don’t, and what follows

What we know today

Established

  • For FDA-approved sildenafil, timing (peak at 30–120 minutes, half-life about 4 hours) and side effects are documented in its label.[1]
  • A single 100 mg dose did not affect sperm motility or shape in healthy volunteers.[1]
  • Kamagra has no FDA application, labeling or NDC listing.[2]

What we don’t know yet

  • How long Kamagra lasts, which side effects it causes and how it affects fertility cannot be known without verified content and studies, which do not exist.[2][3]

Bottom line

Questions about how long Kamagra lasts or how it compares with Viagra assume that both contain the same thing. For approved sildenafil, the answers are precise and published; for Kamagra, they are guesses built on the label of a different product. That gap – not price or brand – is the real difference between them, and it is why the approved medicine is the only one whose effects can actually be predicted.

Sources

  1. FDA: VIAGRA (sildenafil citrate) prescribing information, 2017 (PDF)
  2. openFDA and FDA National Drug Code Directory – no record for Kamagra (iMedix query, accessed September 28, 2026)
  3. FDA: BeSafeRx
  4. FDA: Generic Drug Facts (PDF)

Sources checked October 11, 2026.