What is the main cause of polycystic ovary syndrome?
Polycystic ovary syndrome is a gynecologic disease which is manifested in 65% of cases in women having endocrine infertility. Unfortunately, this syndrome and pregnancy are often incompatible as its clinical manifestation is the lack of ovulation (maturation of ovum and its exit from an ovary). The process of follicles growth and maturation of ovum starts, but doesn't come to the end, and the development of follicles with not matured ovules stops and formation of multiple cysts starts.
Similar pathology can develop also in other bodies. In gynecology it can be ovary polycystosis. However this diagnosis isn't connected with ovary and it is an absolutely different disease which is manifested in the form of cysts on a neck of the uterus.
Forms of ovary polycystosis
- There are two types of polycystosis: primary and secondary.
- At primary ovary polycystosis, symptoms of the disease are shown already during teenage age, most often at 12-13 years. This form badly responds to treatment and is characterized with severe state of the disease.
- Secondary polycystosis appears in women of middle age who were already giving birth are just in a reproductive age or who are in a climax stage. At its secondary form the disease is often followed by various symptoms of metabolic disorders like androginy, excess body weight and increased quantity of insulin in blood owing to dysfunction of pancreas.
- At any type of polycystosis both pregnancy and carrying of a child are possible only after corresponding hormonal treatment (sometimes this treatment is complemented with surgical intervention).
Reasons of polycystic ovary syndrome
1. Hormonal imbalance.
Edocrine system disorders are the most widespread reason of follicular cysts formation. It can be hypothalamus, hypophysis, adrenal glands, pancreas or thyroid gland diseases. Polycystosis it often connected with increased quantity of insulin produced by pancreas. At the same time the excess of insulin influences adrenal glands and forces them to produce more male sex hormone called androgen. The imbalance arising between androgens and estrogen (female sex hormones) causes polycystic ovary syndrome.
2. Infectious diseases
Also severe infectious diseases or frequent colds in the childhood can cause this syndrome. As ovaries and tonsils are closely connected, tonsillitis occurs often in the anamnesis of patients with polycystic ovary syndrome.
3. Hereditary factor
It's proved that genetic predisposition to this disease is often the reason of this syndrome.
4. Stressful situations
Some experts consider that various stressful situations which lead to hormonal failures and subsequent nonovulation can cause polycystosis as well.