Addyi (Flibanserin)

Addyi is used to treat decreased sexual desire in women who have not gone through menopause and who have never had low sexual desire in the past. Flibanserin is a novel multifunctional serotonin agonist and antagonist (MSAA) that improves sexual functioning in premenopausal women who suffer from reduced sexual interest and desire.
Active Ingredient: Flibanserin
Dosage Form: Tablet
Dosage: 100 mg
Minimum Market Price: 4.92

General Information

Addyi is used for treatment of the lowered sexual desire in women who haven't reached the menopause and who had never experienced low sexual desire in the past. Addyi is used only when low sexual desire isn't caused by a medical treatment, a psychological disorder, problems with the self-esteem or use of drugs or other medicals.

Addyi (flibanserin) is available only in certified drugstores within a special program. Addyi is not prescribed to women who have already reached a menopause. This medicine is also not to be used by men.

This medicine was studied in 1995 by a team of researchers at Boehringer Ingelheim Italia in Milan. It was intended to become an antidepressant to affect a person’s mood hormones: serotonin, dopamine, and norepinephrine. It influences the sexual desire and its intensity.

Flibanserin enhances 5-HT1A and inhibits 5-HT2A. Serotonin production in that case is heavily downregulated. It decreases the firing of neurons regulating the release of neurotransmitters, such as dopamine and norepinephrine (which regulate the sexual interest).
Addyi is safe for human consumption although it is designed for women who are premenopausal. It has some side effects which are clearly stated on the label. Addyi is claimed to regulate brain chemicals responsible for sexual desire.

The pills are also only recommended to premenopausal women because they interact with other medical drugs and alcohol, so please consult your doctor before using it. Many women suffer from sexual dysfunction, lack of erotic drive and/or low sexual performance, but aren’t ready to talk about it openly. Sexual dysfunction among women can occur at any age because of different factors. Sexual problems can spoil relationships with a partner. Female enhancement medicine may promote a healthy, active sex life due to the potency of its ingredients increasing sexual sensation, pleasure, arousal and sexual satisfaction.

Addyi can be useful for the treatment of hypoactive sexual disorder in female patients.

  • These pills provide control and regulation of the brain chemicals which are responsible for sexual desire and satisfaction.
  • This medicine inhibits serotonin hormone which lowers sexual activity and boosts the mood of a treated person by decreasing depression and anxiety.

What is Addyi?

Addyi, known generically as flibanserin, is a medication approved for the treatment of premenopausal women with hypoactive sexual desire disorder (HSDD). It's used to address low sexual desire that causes marked distress or interpersonal difficulty and is not due to a medical or mental health condition, problems within the relationship, or the effects of a medication or other drug substance.

How does Addyi work?

Addyi works by affecting the balance of certain chemicals in the brain (neurotransmitters) involved in sexual desire and arousal. Specifically, it acts on serotonin, dopamine, and norepinephrine levels to help increase sexual desire.

What are the common side effects of Addyi?

Common side effects of Addyi include dizziness, sleepiness, nausea, fatigue, insomnia, and dry mouth. These side effects can be serious, leading to a need for immediate medical attention in some cases.

Can alcohol be consumed while taking Addyi?

Alcohol consumption should be avoided while taking Addyi. Drinking alcohol while on Addyi can increase the risk of severe low blood pressure and fainting (syncope), especially within the first few hours after taking the dose.

How is Addyi taken?

Addyi is taken orally, once daily at bedtime. Taking it at night reduces the risk of low blood pressure, fainting, and central nervous system depression such as sleepiness and sedation.

Who should not take Addyi?

Addyi should not be used by women who have gone through menopause, by men, or by children. It's also not recommended for individuals with liver impairment. Those taking certain medications that can increase flibanserin concentration in the blood should avoid it as well.

How long does it take for Addyi to work?

The effects of Addyi are not immediate. It may take several weeks or even months to notice a change in sexual desire and arousal. Individual results can vary.

Can Addyi be taken with hormonal contraceptives?

Yes, Addyi can be taken with hormonal contraceptives. However, it's important to consult with a healthcare provider to understand any potential interactions with other medications.

Is a prescription required for Addyi?

Yes, Addyi is a prescription medication. A healthcare provider needs to evaluate if it's appropriate for a patient's condition before prescribing it.

How should Addyi be stored?

Addyi should be stored at room temperature away from light and moisture. Keep the medication in its original container and out of reach of children and pets.


Don't take alcohol while receiving treatment with Addyi. An interaction of alcohol drinks with this medicine can cause dangerous or undesirable side effects. Grapefruit and grapefruit juice can interact with flibanserin and result in undesirable side effects. Avoid use of products made of grapefruit while taking Addyi.

Avoid intake of the vegetable additives containing ginkgo, resveratrol or goat weed. Addyi can cause thinking or reaction disorders. Avoid driving or equipment operation at least within 6 hours after you took this medicine, if you didn't learn yet how this medicine can influence your reaction. Dizziness or low blood pressure can cause falling or other accidents. Avoid standing up to fast from the sitting or lying position to avoid dizziness. Get up slowly and steadily to prevent falling.

How to take?

  • Take Addyi precisely according to instructions of your MD. Follow all instructions given on the label of the recipe. Don't use this medicine in large or smaller numbers or longer than recommended.
  • Take Addyi only before going to bed.
  • Addyi can reduce the blood pressure and cause dizziness. If you feel not very well after intake of this medicine, you have to lay down.
  • It can take up to 8 weeks before your symptoms improve. Continue to use drugs according to the instruction and tell the doctor if your symptoms don't improve.
  • Usual dose for adults prescribed in case of hypoactive sexual frustration:
  • 100 mg orally once a day before going to bed
  • Therapy duration: this medicine should be stopped after 8 weeks if the patient doesn't report improvement of symptoms.
  • This medicine isn't intended for boosting of sexual activity and is not to be reccomended to women in a postmenopause or to men.
  • This medicine is indicated for treatment of women in a premenopausal period with the acquired, generalized hypoactive frustration of sexual desire (HSDD) which is characterized by low sexual desire which causes the expressed difficulties or interpersonal difficulties and isn't connected with the existing medical or psychiatric state, problems with personal relations or effects of medicines or other medicinal substance.

The medicine is to be stored at the room temperature far from moisture and heat.


Receive the emergency medical care if you have signs of allergic reaction to Addyi: state of anxiety; complicated breathing; face, lips, language or throat edema or dryness.

Immediately call the doctor if you have:

  • heavy drowsiness;
  • strange feeling as if you can disappear.
  • dizziness, drowsiness;
  • fatigue;
  • nausea;
  • dryness in a mouth;
  • problems with night sleep (insomnia).

It is not the complete list of side effects, others disorders can also appear. Ask the doctor about all the possible side effects.


Taking this medicine with other medicines causing sleepiness or lower blood pressure can worsen the effect of Addyi. Ask your doctor before taking Addyi with sleeping pills, pain or muscular relaxation drugs or medicine against cancer, depression or spasms.

Tell the doctor about all the drugs you’re currently taking (especially if you just start or stop using them):

  • cymetidine;
  • Gingko biloba;
  • resveratrol;
  • goatweed
  • nefazodone;
  • heart or blood pressure medicine;
  • antifungal medicine;
  • antiviral medicine;
  • ciprofloxacin, erythromycin, telithromycin;
  • HIV or AIDS medicine.

Other medicines can also interact with flibanserin, including prescribed drugs, vitamins and vegetable products. Not all possible interactions are listed in this article.

Drug and Alcohol

Do not drink alcohol if you take Addyi.


In the case of an ADDYI overdose, an increase in the level or severity of any of the adverse reactions reported above may occur. In this case, treatment should be based on signs and supportive measures as needed. There are no well-known specific antidotes for flibanserin, so you should seek medical aid.

There are certain psychological contraindications concerning treatment with the Addyi. In the first lineit is if a motivation to take this medication comes from the partner of the patient, rather than from the treated person herself.

Addyi is a complicated medicine. Patients don’t have to try it without a consultation with a doctor. A patient should only take Addyi if she has a need to feel sexual after consulting an appropriate specialist.

Follow all the instructions on the label and packing. Report to the medical personnel about all your physical and mental states, an allergy and all the drugs, which you use.


Peter: After my wife became irritable and grumbling, I offered her to try the Addyi). At first she refused to take it. But later she agreed and our intimate life has cardinally changed. Besides, it has positively affected the relations in general! Thanks for such a high-quality medicine!

Helen: When I occasionally saw the correspondence of my husband on the Internet with another woman, I have at once pricked up the ears. At the same time, I understood my fault: my absence of sexual desire. My friend advised me to take the Addyi tablets. This medicine has made the business. I feel desire to the spouse. Now he is keen only on me!

Sarah: There was a difficult period in the family relations, problems at work that caused huge depression. To please myself and my husband I tried the women's Viagra Addyi, after that everything improved up to standard in our sexual experience. The experiments resulted in a heap of new feelings, the mood has considerably improved. And what is interesting against this background the situation at work has gone uphill!

Jenny: The husband has decided to surprise me, he arranged a romantic dinner, and showed me the tablets of Addyi, which he had already bought secretly. At first I doubted the effect of the tablets and forced him to show me information about this medicine on the Internet, I’ve read a lot about it and decided to try one tablet. Of course, I was skeptical, the promised effect appeared not at once, but approximately in 30-40 minutes…Well, I have no regrets that I took a pill!

Lana_153: My husband has presented to me a pack of Addyi, I disagreed to take them at first. But next day he has persuaded me to try them. For relaxation I took a bath, then I took 1 pill) In half an hour I have already felt their effect))) Of course we weren't idle))) and the effect hasn't kept itself waiting, all tactile feelings have been enhanced. Generally I haven't regretted that I agreed to this experiment))) Now when we want to try something unusual, we use these medicines)

Rosy F.: I was trying to please my partner and get some new emotions to refresh our relations so I decided to try the tablets Addyi. I spent a lot of time to find it at the chemists’, and the price wasn’t really low. However I was disappointed by the effect of this medicine because I felt almost no changes. The mood was good, but it seems to me, I was a little bit too sleepy after I took one pill.

Respond: 2
    • You’re welcome! I’m glad you found the information about Addyi (Flibanserin) helpful. Addyi is a medication that is approved to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. It works by affecting certain chemicals in the brain to help increase sexual desire. If you have any further questions or need more information about Addyi, feel free to ask.

Minimum Market Price