Uses & Effectiveness
Overview
Artichoke (Cynara cardunculus) is a plant native to the Mediterranean area. The leaf, stem, and root are used to make extracts, which are used as medicine.
Artichoke is also commonly consumed as a food. It contains chemicals that can reduce nausea and vomiting, spasms, and gas. These chemicals have also been shown to lower cholesterol and protect the liver.
People commonly use artichoke for indigestion and high levels of cholesterol or other fats in the blood. It is also used for high blood pressure, hepatitis C, irritable bowel syndrome (IBS), and many other conditions, but there is no good scientific evidence to support most of these uses.
Don’t confuse artichoke with Jerusalem artichoke (Helianthus tuberosus).
Vitamin K, found abundantly in artichokes, plays a vital role in blood clotting and bone health. Although low in calories, artichokes provide approximately 22% of the recommended daily intake of vitamin K, making them a nutritious addition to any diet.
Side Effects
When taken by mouth: Artichoke is commonly consumed in food. It is possibly safe when taken as a medicine for up to 12 weeks. Artichoke can cause side effects such as gas, upset stomach, and diarrhea. Artichoke might also cause allergic reactions.
Interactions
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Medications changed by the liver (Cytochrome P450 2B6 (CYP2B6) substrates) interacts with ARTICHOKE
Some medications are changed and broken down by the liver. Artichoke might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
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Medications changed by the liver (Cytochrome P450 2C19 (CYP2C19) substrates) interacts with ARTICHOKE
Some medications are changed and broken down by the liver. Artichoke might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
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Medications for diabetes (Antidiabetes drugs) interacts with ARTICHOKE
Artichoke might lower blood sugar levels. Taking artichoke along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
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Medications for high blood pressure (Antihypertensive drugs) interacts with ARTICHOKE
Artichoke might lower blood pressure. Taking artichoke along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.
Moderate Interaction
Be cautious with this combination
Special Precautionsand Warnings
When taken by mouth: Artichoke is commonly consumed in food. It is possibly safe when taken as a medicine for up to 12 weeks. Artichoke can cause side effects such as gas, upset stomach, and diarrhea. Artichoke might also cause allergic reactions. Pregnancy and breast-feeding: There isn’t enough reliable information to know if artichoke is safe to use as a medicine when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.
Bile duct obstruction: Artichoke might worsen this condition. If you have this condition, don’t use artichoke before talking with your healthcare provider.
Allergy to ragweed and related plants: Artichoke may cause an allergic reaction in people who are sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. If you have allergies, be sure to check with your healthcare provider before taking artichoke.
Gallstones: Artichoke might make gallstones worse by increasing bile flow.
Dosing
Artichoke leaf extract has most often been used by adults in doses of 320-640 mg by mouth three times daily. Speak with a healthcare provider to find out what dose might be best for a specific condition.
