Generic Clomid (Clomiphene)

Clomid is aimed at ovulation stimulation in women diagnosed with infertility due to secondary hypo-ovaria, mainly caused by hypothalamic-pituitary disorders. It works by blocking estrogen receptors at the hypothalamus, which is an important "hormonal control center" for the body.
Active Ingredient: Clomiphene
Dosage Form: Tablet
Dosage: 25 mg; 50 mg; 100 mg
Minimum Market Price: 0.2

General Information

Clomid, having Clomiphene as an active ingredient, is not an anabolic steroid, it is a sex hormone (estrogen, obtained synthetically). Clomid today has two ways of application: traditional medicine and sports. Doctors recommend it to women who have difficulty with pregnancy and problems with the ovarian function.

Main idea of the medicine development was to find a universal treatment against breast cancer, but it didn’t work out as expected. So, later it started been using as a medicine to stimulate ovulation in women before pregnancy.

Clomid is an antiestrogenic drug of nonsteroidal structure. It blocks estrogen-sensitive receptors and enhances the secretion of gonadotropic hormones, stimulating maturation of the follicles and the formation of the yellow body. In large doses it inhibits the secretion of gonadotropins. Also it promotes increased testosterone generation in men. In case of high concentration of estrogens it acts as an antiestrogen, and at a low concentration produces an estrogenic effect.

So, the pills can be recommended to women in three cases:

  1. If the absence of ovulation is caused by a pre-diagnosed polycystic ovary syndrome.
  2. If infertility does not have a certain genesis, that is, if with ideal medical indicators a woman still does not get pregnant after more than a year of intense attempts. In this case, the medicine is usually used in combination with an additional drug – metformin, which invokes increase of the level of insulin and promotes the stimulation of ovulation.
  3. If artificial insemination (IVF, ICSI, etc.) requires some guarantees of the procedure success. Although from a medical point of view such application of the drug is not justified enough, many women ask their doctor to include Clomid in their treatment course, since this tablet is considered effective to increasing the chances of becoming pregnant.

Studies and years of experience showed that about 80% of women experiencing problems with ovulation report the release of the ovum from the ovaries even after the first treatment course with the medication. However, only 30% of patients manage to become pregnant immediately after the first treatment course. Nevertheless, a six-month treatment course is considered quite optimal, so that even if you did not get pregnant after this period, you still have great chances to see the needed two bars in the next several months, provided the treatment course is properly applied.

What is Clomid?

Clomid, or clomiphene citrate, is a medication commonly used to treat infertility in women. It works by stimulating ovulation, the process where an ovary releases an egg, in women who do not ovulate regularly or cannot ovulate at all.

How does Clomid work?

Clomid works by blocking estrogen receptors at the hypothalamus, which is an important “hormonal control center” for the body. When estrogen is blocked, the hypothalamus induces the pituitary gland to produce follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which in turn stimulate ovulation.

What are the success rates of Clomid for ovulation and pregnancy?

About 80% of women taking Clomid will successfully ovulate, and between 30% and 40% of all women taking Clomid will become pregnant within three cycles. Success rates vary based on individual health factors and underlying fertility issues.

What are the common side effects of Clomid?

Common side effects of Clomid include hot flashes, mood swings, nausea, breast tenderness, and headaches. Some women may experience bloating and discomfort during ovulation. Rarely, it can lead to more serious side effects like ovarian hyperstimulation syndrome (OHSS).

How is Clomid taken?

Clomid is usually taken by mouth, with a course typically starting at a low dose. The dose may be increased if ovulation does not occur. Clomid is often taken for five consecutive days early in the menstrual cycle, but the exact regimen will depend on individual circumstances and a doctor's recommendation.

Can Clomid cause twins or multiple births?

Yes, taking Clomid increases the likelihood of conceiving twins or multiples, as it can lead to the release of more than one egg during ovulation. The chances of multiple births with Clomid are around 10%.

Is Clomid effective for men?

Clomid can be used off-label to treat male infertility by increasing sperm production, especially in cases of hormonal imbalance. However, its effectiveness in men is less well-established than in women.

How long can you take Clomid?

Typically, Clomid is prescribed for up to six cycles. Prolonged use of Clomid is not recommended, as it may increase the risk of ovarian cancer and other side effects. Regular monitoring and follow-up with a healthcare provider are essential.

Can Clomid help with unexplained infertility?

Clomid is often used as a first-line treatment for women with unexplained infertility, as it can induce ovulation and increase the chances of pregnancy.

What should you do if you miss a dose of Clomid?

If you miss a dose of Clomid, contact your healthcare provider for advice. Do not take a double dose to make up for a missed one.

How to take?

The regimen of the drug application is very simple. As soon as your doctor conducts a full medical examination and issues a prescription for the drug, you can immediately go to the pharmacy. Prior to using the medication you should always consult a doctor about the timing. Usually mentioned tablets are taken on the third-seventh day of the menstrual cycle. Around a week after the beginning of the menstrual cycle, one should lead an active sexual life, preferably followed with one-day break, so that your partner has enough time to accumulate spermatozoa ready for fertilization. If by the tenth day of the menstrual cycle your cervical mucus has a consistency of egg white, that means that you are on the right track, and that ovulation will happen soon. In a week or two, you can start using pregnancy tests and hope for the best.

Side Effects

Side effects of Clomiphene are imperceptible, and do not pose a direct threat to the female body. In the most frequent cases there are abdominal pain, insomnia and weight gain. The worst possible case development can be an appearance of ovarian cysts or the diagnosis of ovarian cancer. Nevertheless, the chance of occurrence of such consequences is really small.

Side effects include:

  • dizziness,
  • headache,
  • drowsiness,
  • slowing of the speed of mental and motor reactions,
  • depression,
  • increased excitability,
  • insomnia,
  • nausea,
  • vomiting,
  • gastralgia,
  • flatulence,
  • diarrhea,
  • caustic rash,
  • allergic dermatitis,
  • vasomotor disorders,
  • rarely – polyuria,
  • increased urination,
  • lower abdominal pain,
  • dysmenorrhea,
  • menorrhagia,
  • ovarian enlargement (including cystic).


Also it should be mentioned that there are some contraindications to the use of these tablets. Those include hypersensitivity to Clomid Online (and any of its components), hepatic and / or renal insufficiency, metrorrhagia of unclear etiology, ovarian cyst, genital neoplasms, pituitary tumor or hypopituitarism, endometriosis, ovarian failure with hyperprolactinemia, as well as pregnancy.
When taking Clomiphene you have to observe a number of specific guidelines, and take into account the possibility of multiple pregnancy development.

Furthermore, Clomid can also be taken by men, but for completely different purposes. Both amateurs and professional athletes use this medication quite often. Athletes often use a variety of other chemicals, such as anabolic steroids, hCG, tamoxifen, thyroid hormones, etc. As opposed to other anabolic steroids or hormones, the drug does not lower testosterone level. Conversely by LH burst, it increases the level of testosterone.

Almost all anabolic steroids possess both androgenic and anabolic properties. In some cases, anabolic steroids contribute to the formation of estrogens. Facilitated by the enzyme the aromatase also turns into a female sex hormone, estrogen. Estrogen promotes the development of gynecomastia in bodybuilders. Although bodybuilders love to demonstrate their body hardly any of them will want to show a womanlike breast. Therefore, the medication is used to block the development of gynecomastia. By blocking the estrogen receptors, it prevents the development of gynecomastia caused by anabolic steroids.

When Clomiphene blocks estrogen receptors in the brain, the hypothalamus causes a LH and FSH burst – hormones release, which leads to an increase in sex hormones synthesis. LH and FSH also affect the testes, causing a further testosterone synthesis. Testosterone gives an athlete an additional impulse. Some bodybuilders take Comid only to get an anabolic effect. Others use it in combination with other steroids and growth hormone.

Clomid is taken only once a day. Specialists in the field of bodybuilding are advised to take it alone or in combination with anabolic steroids of low activity. Most bodybuilders take anabolic steroids for several months and then switch to Clomiphene. The substance provides a burst of testosterone. The exact time when you should start taking the medicine cannot be told precisely. But still there is a recommendation to start taking it on 7th-10th day after the last day of taking steroid drugs.

A lot of athletes and bodybuilders take this substance but they use different doses. There are no medical recommendations for taking these pills to those who are doing this for bodybuilding. However the dosage was established by practical means. Most bodybuilders take clomiphene for two weeks 50-100 mg per day. Some bodybuilders recommend increasing the dose up to 100 mg per day. Do not take the medication for more than three weeks. This periodicity was established by bodybuilders of the past. Since doctors do not generally recommend taking substance to bodybuilders, it is very difficult to get a medical advice on this medication intake regimen. In any case, if there are doubts, you can consult with specialists on infertility treatment: they know the effect of this drug best of all.
It is not known exactly how long it takes to take Clomiphene. There is no evidence of long-term treatment with these tablets. There is only a general recommendation that Clomid should not be taken longer.

If you take the drug for a short period of time and adhere to the indicated doses, then it is completely safe. Most of the adverse reactions caused by it are temporary and disappear after discontinuation.

The main side effects are:

  • flush of blood to the face
  • abdominal discomfort
  • nausea, vomiting
  • pain in the chest
  • headache
  • abnormal vaginal bleeding
  • general fatigue
  • hair loss

Another serious side effect is mood change. Many reports state that women who have been taking Clomid for a long time develop a variety of behavioral problems. It can be deep depression, irritability, anxiety or aggression. There have also been cases of paranoia, anxiety and insomnia.

Despite such unpleasant complications in some people, studies conducted in many clinics showed that this occurs only in 1% of women taking the medication. There are no data on how many bodybuilders experience similar side effects.

Clomiphene containing treatment can easily be bought by anyone. However, all sports organizations prohibit its use in professional sports. The substance is easily detected in urine, for 5 to 12 days after its use at least. Clomiphene tests are very well developed, and some laboratories even measure testosterone and estrogen levels, their metabolites and determine the percentage rate. In case of detection of certain rates the use of the mentioned substance is suspected.


Compliance with the rules for taking Clomiphene can bring positive results to both men and women, as evidenced by the following reviews:

Owing to the course of treatment with this drug a long-awaited pregnancy has come. I'm happy!

These pills are effective! A friend of mine could not get pregnant for 6 years, the doctor prescribed Clomid. A month later she became pregnant!

Teresa: Doctors recommended various means for stimulating ovulation. And only these tablets led to pregnancy.

This product shows an excellent result. Increase in weight and strength is really obvious. I'm satisfied.

Tom: I'm very pleased with the result. After the course of steroids the level of testosterone was quickly restored with the help of the drug, practically with no loss of muscle mass.

Dan: I recommend this treatment to those who want to restore their own testosterone production as soon as possible and at the same time to prevent any large loss of mass and strength. Works great!

Respond: 2
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