Uses & Effectiveness
We currently have no information for PHENIBUT overview.
Overview
Phenibut is a chemical similar to a brain chemical called gamma-aminobutyric acid (GABA). It’s used recreationally and as a drug in Russia. It may be unsafe.
Phenibut might decrease anxiety and have other effects on the body, but most research on phenibut has been published in Russia.
People use phenibut for anxiety, alcohol use disorder, insomnia, depression, stress, and many other conditions, but there is no good scientific evidence to support these uses.
Phenibut is approved for use in Russia and some Eastern European countries. Due to safety concerns, it’s not approved in the US for use in dietary supplements. Don’t confuse phenibut with GABA. These are not the same.
Phenibut is a nootropic compound known for its calming and anxiolytic effects, believed to promote better sleep, reduce stress, and increase cognitive function, making it a popular supplement for those seeking improved focus and relaxation.
Side Effects
When taken by mouth: Phenibut is likely unsafe. Phenibut can cause many side effects, including reduced consciousness, dizziness, nausea, poor balance, and fatigue. Taking large doses can cause trouble breathing, unconsciousness, and death.
Phenibut can cause dependence. People who use phenibut for 3 days or more and then stop taking it might experience withdrawal symptoms. These symptoms can include decreased appetite, nausea, muscle aches, fast heart rate, anxiety, agitation, trouble sleeping, and seizures.
Interactions
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Pregabalin (Lyrica) interacts with PHENIBUT
Phenibut acts on the brain in a similar way to pregabalin. Taking these two chemicals together might increase the risk for side effects.
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Sedative medications (CNS depressants) interacts with PHENIBUT
Phenibut might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking phenibut with sedative medications might cause breathing problems and/or too much sleepiness.
Moderate Interaction
Be cautious with this combination
Special Precautionsand Warnings
When taken by mouth: Phenibut is likely unsafe. Phenibut can cause many side effects, including reduced consciousness, dizziness, nausea, poor balance, and fatigue. Taking large doses can cause trouble breathing, unconsciousness, and death.
Phenibut can cause dependence. People who use phenibut for 3 days or more and then stop taking it might experience withdrawal symptoms. These symptoms can include decreased appetite, nausea, muscle aches, fast heart rate, anxiety, agitation, trouble sleeping, and seizures.
Pregnancy and breast-feeding: There isn’t enough reliable information to know if phenibut is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Dosing
Despite being banned in the US, phenibut is still found in some dietary supplements. Most products containing phenibut are sold online. Taking phenibut is unsafe and can lead to dependence and withdrawal.
