PROCAINE

PROCAINE
Procaine is a local anesthetic commonly used in dentistry. It works by blocking nerves impulses and can provide temporary pain relief during various procedures.
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Uses & Effectiveness

Effective for

  • Pain reduction during surgery. Procaine injection is an FDA-approved prescription product used as a local anesthetic.

Overview

Procaine is a chemical. People use it for medicine. Be careful not to confuse the procaine used by mouth with the prescription procaine given by injection only under the supervision of a healthcare professional.

Procaine is most often used as an anti-aging agent for conditions such as dementia, age-related decline in memory and thinking skills, quality of life, and many others, but there is no good scientific evidence to support these uses.

As a prescription-only injection, procaine is used for local anesthesia.

Procaine is not a vitamin. It is actually a local anesthetic that was first synthesized in 1905 by a German chemist named Alfred Einhorn, who coined the term Novocaine. It was widely used as a dental anesthetic until more modern alternatives were developed.

Side Effects

When taken by mouth: It is not known whether procaine is safe when taken by mouth. It can cause some side effects including heartburn, migraines, and a serious condition called systemic lupus erythematosus (SLE). SLE causes a variety of symptoms including joint pain, rashes, lung problems, and many other symptoms.

When given as a shot: Procaine is safe when the prescription-only product is given as a shot by a healthcare professional as a local anesthetic.

Interactions

    Major Interaction

    Do not take this combination

  • Digoxin (Lanoxin) interacts with PROCAINE

    Digoxin (Lanoxin) helps the heart beat more strongly. Digoxin (Lanoxin) can also control how fast the heart beats. Getting a procaine injection can slow the heartbeat. Taking digoxin with procaine might cause your heartbeat to be too slow.

  • Muscle relaxants interacts with PROCAINE

    Procaine is given as a shot to numb pain. Taking procaine with some muscle relaxants can cause the numbing to last too long. Before getting a procaine injection tell your doctor if you are taking any muscle relaxants.

    Some of these muscle relaxants include atracurium (Tracrium), pancuronium (Pavulon), succinylcholine (Anectine), and others.

  • Succinylcholine interacts with PROCAINE

    Procaine is injected and used to numb pain. Taking procaine with succinylcholine can cause the numbing to last too long.

    Moderate Interaction

    Be cautious with this combination

  • Aminosalicylic acid interacts with PROCAINE

    The body breaks down procaine to get rid of it. Procaine is broken down to a chemical called aminobenzoic acid. Aminobenzoic acid might decrease the effectiveness of aminosalicylic acid. Taking procaine along with aminosalicylic acid might decrease the effectiveness of aminosalicylic acid.

  • Antibiotics (Sulfonamide antibiotics) interacts with PROCAINE

    The body changes procaine to para-aminobenzoic acid (PABA). PABA can decrease the effectiveness of certain antibiotics called sulfonamides.

    Some of these antibiotics include sulfamethoxazole (Gantanol), sulfasalazine (Azulfidine), sulfisoxazole (Gantrisin), and trimethoprim/sulfamethoxazole (Bactrim, Septra).

Special Precautionsand Warnings

When taken by mouth: It is not known whether procaine is safe when taken by mouth. It can cause some side effects including heartburn, migraines, and a serious condition called systemic lupus erythematosus (SLE). SLE causes a variety of symptoms including joint pain, rashes, lung problems, and many other symptoms.

When given as a shot: Procaine is safe when the prescription-only product is given as a shot by a healthcare professional as a local anesthetic. Pregnancy and breast-feeding: It's LIKELY UNSAFE to use procaine for self-medication if you are pregnant. If you are breast-feeding, it is also best to avoid using procaine. Not enough is known about how it might affect the nursing infant.

Myasthenia gravis, a progressive disease that weakens the muscles: If you have myasthenia gravis, you should not be given procaine intravenously (by IV).

Pseudocholinesterase deficiency, an inherited disorder: People with this disorder are sensitive to certain anesthetic drugs. If you have this disorder, you should not be given procaine by injection.

Systemic lupus erythematosus (SLE): Procaine might make this condition worse. Don't use procaine if you have SLE.

Dosing

The following doses have been studied in scientific research:

BY INJECTION:

  • For local anesthesia. The prescription-only product is given as a shot by a healthcare professional.
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