- 1. General information
- 2. The main ingredient
- 3. The effect of the drug
- 4. Interactions
- 5. Precautions
- 6. The has a list of contraindications:
- 7. Doxycycline dosage
- 8. Doxycycline and side-effects
- 9. The effectiveness of the drug reducing because of the following reasons:
- 10. Doxycycline and alcohol
- 11. Contact of antibiotic molecules with alcohol can lead to intoxication. Indicants of intoxication:
Antibiotics (anti – “against” + bios – “life”) are chemical compounds of biochemical origin.
New effective generations of natural and semisynthetic antibiotics are entering the market every day. Semisynthetic antibiotics are targeted at pathogenic microbes and some malignant neoplasms.
The main ingredient
Vibramycin (Doxycycline Hyclate) belongs to the family of semisynthetic antibiotics. The main component of the medicine is Doxycycline.
This active constituent was obtained in 1960 and belongs to the group of tetracycline antibiotics. These are the most effective antimicrobial drugs to date.
Doxycycline shows a high bacteriostatic activity. This was achieved through chemical synthesis. The medicine permeates into the cell and disrupts the protein production in it.
The microorganism loses its activity, mating ability and dies. In addition, doxycycline manifests less toxicity to the human body than other antibiotics.
The effect of the drug
Firstly, Vibramycin (Doxycycline Hyclate) has an effect on a large signature of microbes. The medicine belongs to the class of broad-spectrum antibiotics. A disease can happen because of hundred different bacterias.
Secondly, Doxycycline acts on such dangerous bacteria as staphylococcus and streptococcus, above all Shigella dysenteriae and salmonella.
Also, infectious agents of gonorrhea and syphilis and many others.
Thirdly, most importantly, the medicine acts on rickettsia (intracellular parasites) and on an insidious microbe called mycoplasma. The active substance of the medicine is also effects the reproduction of chlamydia.
The drug was made by a group of enthusiast, who were making experiments with the existing antibiotics, and they were trying to solve the problem of the global tolerance, spreading quickly throughout the globe.
This medical preparation also can help you to get rid of many several deceases:
- sacred fire
- infectious otitis
- gastrointestinal tract infections
- whooping cough
- malignant anthrax
- cholera and hundreds of other diseases
The medicine made to prevent Japanese river fever, traveler's diarrhoea, canicola fever and pollen allergy.
Vibramycin (Doxycycline Hyclate) is manufactured in the form of tablets and each contains 100 mg of active component, besides there also capsules, syrup and ampoules in the market.
It is undesirable to use the medicine during pregnancy, because doxycycline can produce toxic effects on fetal development (and delay in the development of the skeleton). It is prescribed in exceptional cases.
The active component of Vibramycin (Doxycycline). Besides, do not use the drug during breast-feeding because breast contains a lot of calcium.
It is strictly forbidden to use the medicine for children under 8. It is undesirable to prescribe the medicine to children younger than 12.
The active substance of the medicine has a photosensitizing effect, due to this, it increases the sensitivity of the organism to ultraviolet irradiation. Therefore, the patient should avoid exposure to sunlight and use cosmetic sunscreeners during treatment. During san bathing you might have an undesirable effect, because sun can produce skin pigmentation on the face and other unpleasant consequences.
The has a list of contraindications:
- allergy to the active ingredient (Doxycycline)
- hematoporphyria and severe liver impairment
- renal insufficiency
The patient should inform attending medical doctor if he or she has at least one of the diseases. Periodic monitoring of the liver and hematopoiesis is necessary in case of a long use of the drug.
The average daily dosage for adult patients is 200 mg of active substance , so it can be 2 tablets at the beginning of treatment. After you can administrate a maintenance dose of 100 mg (which is 1 tablet). Please, note that for each disease and condition of the patient there is an individual scheme and duration of treatment.
If the patient miss a regular capsule intake, he (she) must take the dose which he missed as soon as possible, otherwise he will lower the effect of the drug. It is always better to have a special schedule from drug intake, because our organism can fight the disease much easier in this case.
Doxycycline and side-effects
The following side effects are possible:
- hemolytic anemia
- anaphylactic reactions
- headache and tinnitus
- abdominal pain, besides: nausea, vomiting, diarrhea and indigestion
- allergic reaction to the ingredients of the drug: itching and skin rash
- photosensitivity, also Quincke's edema
- escalation of the residual blood nitrogen candidiasis
- intestinal dysbiosis
- changing the color of teeth in children
The risk of allergic reactions is much less than when using antibiotics of the penicillin and cephalosporin groups, therefore try not to combines these medicines same time.
The effectiveness of the drug reducing because of the following reasons:
- methylated alcohol
- diphenylhydantoin and other boosters of microsomal oxidation
Doxycycline and alcohol
Vibramycin (Doxycycline Hyclate), like other antibiotics, can not be used with alcohol. Taking a drug with alcohol can lead to a disulfiram-like reaction.
Contact of antibiotic molecules with alcohol can lead to intoxication. Indicants of intoxication:
- sicchasia and vomiting
- severe headaches, besides that migraines (for those who often suffer of it)
- fever, also redness of the chest, face and neck
- heavy and intermittent breathing
- cramps in the arms and legs.
You should not use alcoholic drinks during the period of taking drug from three days to one month because in this case you are loosing the effectiveness of the drug.