For many cancer patients, pain is an overwhelming burden, often poorly controlled despite conventional treatments. Now, new research suggests that virtual reality (VR) technology may offer a revolutionary approach to pain relief, providing a non-invasive, drug-free alternative that could enhance quality of life.

In a study recently published in Scientific Reports, cancer patients who used VR headsets to explore immersive underwater environments reported a significant reduction in pain levels. These self-reported improvements were backed by advanced brain imaging, which revealed substantial changes in how pain-related neural circuits communicate within the brain.

“This marks a significant shift in pain management,” said lead researcher Somayeh Besharat Shafiei, assistant professor of oncology at Roswell Park Comprehensive Cancer Center in Buffalo, NY. “The ability to harness neuroimaging and digital therapeutics could revolutionize how we assess and treat pain, offering an alternative to opioids and improving patient outcomes.”

Uncontrolled pain affects up to 80% of cancer patients, with nearly half experiencing severe pain in later stages. Distraction is a known technique for pain relief, engaging the brain in alternative stimuli to lessen the perception of discomfort. To test whether VR could effectively serve this purpose, researchers conducted an experiment involving 41 cancer patients.

Participants wore VR headsets and explored a visually rich underwater world while donning specialized caps that recorded brain activity through functional near-infrared spectroscopy (fNIRS). This allowed scientists to objectively measure pain circuit responses in real-time. Their results were compared to 13 healthy individuals and 93 cancer patients who underwent similar monitoring without VR.

The findings were striking: More than 75% of VR participants reported pain reductions exceeding the clinically significant threshold of 30%. Meanwhile, brain imaging confirmed that VR altered communication within pain-processing networks, further validating patients’ self-reports.

“These findings suggest that VR could serve as a powerful, non-invasive tool for pain management in cancer patients,” the researchers concluded. “With further research, VR-based therapies could become a standard component of integrative pain treatment, reducing dependence on opioid medications and improving overall patient well-being.”

As medical professionals seek new ways to combat chronic pain while minimizing opioid use, VR technology may emerge as a transformative force in oncology care, offering a safe, effective, and immersive approach to pain relief.