Key Facts
- Cialis works by improving blood flow to the penis, but it only works when you are sexually aroused. It does not create desire.
- Its main advantage is its long duration, lasting up to 36 hours, which allows for more spontaneity.
- There are two ways to use it: a higher dose taken as needed, or a lower dose taken every single day.
- Unlike some other ED pills, Cialis is not significantly affected by food.
- An erection lasting more than 4 hours (priapism) is a rare but serious side effect that requires immediate medical attention.
On This Page:
How Cialis Actually Works (It’s Not a Magic Switch)
I prescribe Cialis (tadalafil) frequently in my practice for treating erectile dysfunction. It’s an excellent medication, but a lot of men have misconceptions about how it works. Let’s clear that up. Cialis is not an “on” switch for an erection. It’s more like a tool that makes your body’s natural processes work much better.
When you’re sexually aroused, your body releases chemicals that relax the blood vessels in the penis, allowing blood to rush in. Cialis works by helping those blood vessels stay relaxed longer, which improves blood flow and helps you achieve and maintain a firm erection. The key takeaway is this: you still need that initial spark of arousal. The pill just helps your body follow through.
The Two Dosing Strategies: As-Needed vs. Daily
One of the best features of Cialis is its flexibility. We can tailor the approach to your lifestyle. I have a more detailed article comparing Cialis daily vs as needed, but here is a quick breakdown.
| Feature | As-Needed Use (The “Weekend Pill”) | Daily Use (The “Spontaneity Pill”) |
|---|---|---|
| The Idea | You take a pill at least 30-60 minutes before you anticipate sexual activity. | You take a much lower dose pill at the same time every day. |
| Typical Dose | 10 mg is a common start, but can be adjusted from 5 mg to 20 mg. | 2.5 mg or 5 mg. |
| Pros | Great for men who have sex less frequently and prefer not to take a pill every day. One pill can last up to 36 hours. | The medication is always in your system, so you are ready for intimacy at any time, without planning. |
| Cons | Requires some planning, which can reduce spontaneity. | You must remember to take it daily. Not recommended for men with severe kidney issues. |
Timing Is Everything: Getting the Best Results
If you’re using the as-needed dose, timing is crucial. I tell my patients to take it at least 30 minutes before sex, but to understand that it can take up to two hours for the medication to reach its peak concentration in your blood. So, give it time. Don’t take a pill and expect instant results 10 minutes later.
- What about food? Here’s a big plus for Cialis: you can take it with or without food. Unlike sildenafil (Viagra), a heavy, fatty meal won’t significantly delay its effects.
- What about alcohol? I advise moderation. A glass of wine is fine, but heavy drinking can counteract the effects of Cialis and is a cause of ED in its own right. It can also increase the risk of side effects like dizziness.
Dealing with Side Effects
Most men tolerate Cialis very well, but like any medication, it can have side effects. The most common ones are usually mild and temporary.
- Headache and Flushing: This is due to the blood vessel-relaxing effects. Staying well-hydrated often helps.
- Indigestion or Acid Reflux: An over-the-counter antacid can often manage this.
- Back Pain and Muscle Aches: This is a side effect more unique to Cialis. It usually occurs 12 to 24 hours after a dose and resolves within 48 hours. An OTC pain reliever like acetaminophen can be helpful.
For a complete list, see my guide to ED medication side effects. If any side effect is severe or doesn’t go away, we need to talk. We might just need to lower your dose.
Critical Safety Warning: Drug Interactions
This is the most important part of this guide. Some medications create dangerous interactions with Cialis. Let me be perfectly clear: you must never take Cialis if you are taking any form of nitrate medication, which is often prescribed for chest pain (angina). Drugs like nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate, when combined with Cialis, can cause a sudden, life-threatening drop in blood pressure.
You also need to be cautious if you are taking alpha-blockers (often for an enlarged prostate or high blood pressure). Combining them can also lower your blood pressure. I will always review your full medication list before prescribing Cialis to avoid these serious Cialis interactions. Honesty about every medication and supplement you take is essential for your safety.