Ulesfia Lotion

Ulesfia Lotion
Ulesfia Lotion
Ulesfia Lotion is a prescription medication used to treat head lice infestations. It works by suffocating and killing the lice and their eggs.
Active Ingredient: Benzyl alcohol
Minimum Market Price: 0.1

Side Effects

Irritation, itching, redness, tingling, or numbness at the application site may occur. Eye irritation may occur if the medication gets into the eyes . If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

How long does it take for this medicine to take effect?

Ulesfia Lotion begins to take effect immediately upon application by physically obstructing the lice's respiratory spiracles and potentially dissolving the waxy exoskeleton of lice, leading to their dehydration and death. However, the lotion must be left on the hair and scalp for 10 minutes before rinsing, as per the product instructions.

How long do the effects of this medicine last?

The effects of Ulesfia Lotion are mechanical rather than biological, so the effectiveness is immediate for lice present at the time of application. Because it does not kill lice eggs (nits), a second application is recommended 7 days after the first treatment to manage any newly hatched lice. The absence of a neurotoxic mode of action means there's no residual effect to prevent new infestations.

Is it safe to consume alcohol while taking this medicine?

There are no known interactions between systemic alcohol consumption and the topical application of Ulesfia Lotion. However, general health guidelines advise moderation in alcohol consumption.

Is this a habit forming medicine?

Ulesfia Lotion is not habit-forming. It does not contain substances that lead to physical or psychological dependence. It is used externally and specifically for the treatment of head lice infestation.

Can this medicine be taken during pregnancy?

There are limited studies on the use of Ulesfia Lotion during pregnancy. Given its minimal systemic absorption, Ulesfia Lotion is considered low risk; however, as with all medications during pregnancy, it should be used only if clearly needed and after consulting a healthcare provider to weigh the potential risks and benefits.

Can this medicine be taken while breast-feeding?

There is limited information on the excretion of benzyl alcohol, the active ingredient in Ulesfia Lotion, into human milk or its effects on a breastfed child. Considering the minimal systemic absorption of benzyl alcohol from topical application, Ulesfia Lotion is likely to be low risk to a breastfed infant. Still, it is advisable for nursing mothers to consult a healthcare provider before using the lotion to ensure safety.


This medication is used to treat head lice, tiny insects that live on and irritate your scalp.This drug is not recommended for use in children younger than 6 months.

How to use Ulesfia Lotion

Read the Patient Information Leaflet if available from your pharmacist before you start using benzyl alcohol and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is for use on the hair and scalp only. Use this medication as directed by your doctor, usually for 2 treatments, one week apart. Since this medication does not get rid of the lice eggs, it is important to have the second treatment to treat any lice that might have hatched. To help you remember, mark the date on the calendar when you need to use this medication again.

An adult should help you apply this medication. Cover your eyes with a towel and keep your eyes tightly closed while the medication is being applied. The medication should be applied to dry hair and enough medication should be used to cover your entire scalp and hair (including behind the ears and on the back of the neck). Massage the medication into your hair and scalp. Avoid getting the medication in your eyes, mouth, nose, or vagina. If the medicine gets in any of these areas, flush with plenty of water. Leave the medication on your hair as directed by your doctor, usually for 10 minutes, then rinse with water. Wash your hands after using this medication. You can shampoo your hair right after treatment. A fine-tooth comb or lice comb may be used afterward to help remove the treated lice and lice eggs (nits).

Tell your doctor if your condition lasts or gets worse.


Before using benzyl alcohol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Constant or forceful scratching of the skin/scalp may lead to a bacterial skin infection. Tell your doctor right away if you develop worsening redness or pus.

Children may be more sensitive to the side effects of the drug. If you are treating an infant, make sure to tell the doctor if your infant was born early (premature) so that the doctor can decide if your infant is old enough to use this medication.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.


This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Do not share this medication with others.

To avoid spreading lice to other people or getting them again, all recently worn/used (within 2 days before treatment) head wear, scarves, clothing, towels, pillow cases, and bed linens should be machine-washed with hot water and dried in a dryer (at high setting) for at least 20 minutes. For items that cannot be washed, the items may instead be dry cleaned, sealed in a plastic bag for 2 weeks, or sprayed with a disinfectant that kills lice. Brushes, combs, and hair clips should be soaked in hot water (hotter than 130 degrees F/54 degrees C) for 10 minutes, soaked in alcohol for 1 hour, or thrown away. Furniture and floors should be thoroughly vacuumed.

People who are in close contact with the infected person (such as family members in the same household) should also be checked for lice and nits. Treatment may be considered to prevent lice in these people.

It is important to use each dose of this medication as scheduled. If you miss the second dose, ask your doctor or pharmacist right away for further instructions.

Store at room temperature. Do not freeze medication. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

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